LONGOVITAL IN THE PREVENTION OF RECURRENT APHTHOUS ULCERATION

被引：25

作者：

PEDERSEN, A

HOUGEN, HP

KLAUSEN, B

WINTHER, K

机构：

[1] INST FORENS MED,COPENHAGEN,DENMARK

[2] BARTHOLIN INST,COPENHAGEN,DENMARK

[3] HVIDOVRE UNIV HOSP,DEPT CLIN CHEM,DK-2650 HVIDOVRE,DENMARK

[4] FREDERIKSBERG UNIV HOSP,DK-2000 COPENHAGEN,DENMARK

[5] ROYAL DENT COLL,DEPT MICROBIOL,DK-2100 COPENHAGEN,DENMARK

来源：

JOURNAL OF ORAL PATHOLOGY & MEDICINE | 1990年 / 19卷 / 08期

关键词：

aphthae; herbs; LongoVital; mouth; diseases; prophylaxis; stomatitis; vitamins;

D O I：

10.1111/j.1600-0714.1990.tb00862.x

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

LongoVital (LV) (DK. Reg. No. 5178/75) is a herbal based tablet enriched with recommended doses of vitamins. The present study was undertaken to investigate prevention of recurrent aphthous ulceration (RAU) during 6 months' daily intake of LV as compared with placebo in a double‐blind, randomized clinical, cross‐over 1‐yr study. The population comprised 29 otherwise healthy minor RAU patients (18 F, 11 M), mean age 36 (18–67), with an estimated average number of recurrences the previous year of 12.8 (3–30). The number of recurrences was significantly reduced on LV the latter 4 of the 6 months (P<0.01) where 31% were totally free of recurrences. Subjective all‐over evaluation of treatment period was significantly in favor of LV. LV induced no adverse reactions and is the first harmless systemic treatment which has proved better than placebo in the prevention of RAU. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：371 / 375

页数：5

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