ANTIGEN TRANSPORT BY INTESTINAL M-CELLS

被引：7

作者：

AMERONGEN, HM

LANGERMANN, S

机构：

[1] Department of Anatomy, College of Medicine, University of Arizona, Tucson

来源：

CURRENT OPINION IN GASTROENTEROLOGY | 1992年 / 8卷 / 06期

关键词：

D O I：

10.1097/00001574-199212000-00015

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

M cells play a critical role in the generation of protective secretory immunity against intestinal pathogens. For this reason, they have become an important focus for studies on oral vaccine development. In this review, we outline the work on M cells reported in the past year, with particular emphasis on findings that have relevance to vaccine development. The most important findings in this regard are the demonstration of antibody-enhanced M-cell targeting and the analysis of increased M-cell numbers in response to Salmonella infection.

引用

页码：983 / 987

页数：5