THE POLYMERASE CHAIN-REACTION IN HISTOPATHOLOGY

被引：33

作者：

PAN, LX

DISS, TC

ISAACSON, PG

机构：

[1] Department of Histopathology, University College London Medical School, London

来源：

HISTOPATHOLOGY | 1995年 / 26卷 / 03期

关键词：

POLYMERASE CHAIN REACTION; HISTOPATHOLOGY;

D O I：

10.1111/j.1365-2559.1995.tb01434.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Thanks to the advent of the polymerase chain reaction (PCR) molecular genetic study of histological samples is now a relatively straightforward task and the vast histopathology archives are now open to molecular analysis. In this review we outline technical aspects of PCR analysis of histological material and evaluate its application to the diagnosis and study of genetic, infectious and neoplastic disease. In addition, we describe a number of newly developed methods for the correlation of PCR analysis with histology, which will aid the understanding of the molecular basis of pathological processes.

引用

页码：201 / 217

页数：17

共 226 条

[1]

ABBOTT CM, 1993, PRENATAL DIAG, V13, P544

[2] APPLICATION OF THE POLYMERASE CHAIN-REACTION TO THE EPIDEMIOLOGY OF PATHOGENIC AND NONPATHOGENIC ENTAMOEBA-HISTOLYTICA [J].