SULFADOXINE PYRIMETHAMINE OR CHLOROQUINE CLINDAMYCIN TREATMENT OF GABONESE SCHOOL-CHILDREN INFECTED WITH CHLOROQUINE-RESISTANT MALARIA

被引：27

作者：

METZGER, W

MORDMULLER, B

GRANINGER, W

BIENZLE, U

KREMSNER, PG

机构：

[1] ALBERT SCHWEITZER HOSP,INT RES LAB,LAMBARENE,GABON

[2] INST TROP MED,D-10179 BERLIN,GERMANY

[3] UNIV VIENNA,DEPT INFECT DIS,A-1090 VIENNA,AUSTRIA

来源：

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1995年 / 36卷 / 04期

关键词：

D O I：

10.1093/jac/36.4.723

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

a randomized trial, a high dosage chloroquine monotherapy (45 mg/kg over 3 days) was compared with combination regimens of sulfadoxine/pyrimethamine and chloroquine/clindamycin for treating Gabonese school children with Plasmodium falciparum malaria. In chloroquine treated patients only 32% were ultimately cured. In contrast, more than 90% of patients were cured after treatment with either combination regimen.

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收藏

页码：723 / 728

页数：6

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