ALKALOIDS IN ANIMAL AND HUMAN TISSUES .6. SYNTHESIS AND ABSOLUTE-CONFIGURATION OF CHIRAL 2,3,10,11-TETRAHYDROXY-8-METHYL-BERBINES [3]

被引：30

作者：

BRUDERER, H

METZGER, J

BROSSI, A

DALY, JJ

机构：

[1] F HOFFMANN LA ROCHE & CO AG, PHARM FORSCHUNGSABT, BASEL, SWITZERLAND

[2] F HOFFMANN LA ROCHE & CO AG, ZENT FORSCHUNGSEINHEITEN, BASEL, SWITZERLAND

来源：

HELVETICA CHIMICA ACTA | 1976年 / 59卷 / 08期

关键词：

D O I：

10.1002/hlca.19760590818

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis and absolute configuration of the 4 optically active stereoisomers of the title compound are described. These compounds constitute potential alkaloids obtained by condensation of either R-(+) or S-(-)-norlaudanosoline with acetaldehyde, a major metabolite of ethanol.

引用

页码：2793 / 2807

页数：15

共 20 条

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