HIGH-SENSITIVITY, TOTAL-BODY PET SCANNING USING 3D DATA ACQUISITION AND RECONSTRUCTION

被引:16
作者
CHERRY, SR
DAHLBOM, M
HOFFMAN, EJ
机构
[1] Division of Nuclear Medicine & Biophysics, UCLA School of Medicine, Los Angeles, CA
基金
美国国家卫生研究院;
关键词
D O I
10.1109/23.159765
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
2D total body PET studies generally suffer from poor and hon-uniform signal-to-noise (S/N) properties, which are consequences of i) the limited scanning time at each axial position and ii) the difference in direct and cross plane sensitivity. By combining 3D data acquisition and reconstruction with a quasi-continuous axial bed motion, gains in S/N of around 2 (equivalent to a sensitivity gain of 4) can be achieved for typical whole body activity concentrations. S/N uniformity is also considerably improved. In vivo studies further illustrate the improvement in image quality due to 3D data collection. However, the routine implementation of 3D total body imaging will require efficient ways of handling the vast amounts of data produced by these studies.
引用
收藏
页码:1088 / 1092
页数:5
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