POLYMERS FOR CONTROLLED PARENTERAL DELIVERY OF PEPTIDES AND PROTEINS

被引：79

作者：

HELLER, J

机构：

[1] Controlled Release and Biomedical Polymers Department, SRI International Menlo Park, CA

来源：

ADVANCED DRUG DELIVERY REVIEWS | 1993年 / 10卷 / 2-3期

关键词：

PROTEIN RELEASE; BIOERODIBLE HYDROGELS; BIOERODIBLE POLYMER; LACTIDE GLYCOLIDE COPOLYMERS; POLYANHYDRIDES; POLY(ORTHO ESTERS); VACCINES; REGULATED DRUG DELIVERY;

D O I：

10.1016/0169-409X(93)90047-8

中图分类号：

R9 [药学];

学科分类号：

1007 [药学];

摘要：

This review summarizes the current state of parenteral delivery of proteins and peptides. Although an attempt has been made to provide a comprehensive review, the more recent developments, such as delivery of LHRH analogues, vaccine delivery systems and regulated systems, have been emphasized. Non-regulated delivery systems have been divided into non-degradable and degradable and each has been subdivided into hydrophilic and hydrophobic systems. Regulated systems have been divided into externally regulated and self-regulated.

引用

页码：163 / 204

页数：42

共 114 条

[1]

CONTROLLED-RELEASE VACCINES - BIODEGRADABLE POLYLACTIDE POLYGLYCOLIDE (PL/PG) MICROSPHERES AS ANTIGEN VEHICLES [J].