FAT EMULSIONS IN PARENTERAL-NUTRITION AFTER LIVER-TRANSPLANTATION - THE RECOVERY OF THE ALLOGRAFTS RES FUNCTION AND HISTOLOGICAL OBSERVATIONS

被引:11
作者
KUSE, ER
KEMNITZ, J
KOTZERKE, J
WASSMANN, R
GUBERNATIS, G
RINGE, B
PICHLMAYR, I
机构
[1] Zentrum Anästhesiologie, Abt. IV, Medizinsche Hochschule Hannover, 3000 Hannover 61
[2] Pathologisches Institut, Medizinsche Hochschule Hannover, 3000 Hannover 61
[3] Abteilung Nuklearmedizin und spezielle Biophysik, Medizinsche Hochschule Hannover, 3000 Hannover 61
[4] Abteilung für Abdominal- und Transplantationschirurgie, Medizinsche Hochschule Hannover, 3000 Hannover 61
关键词
D O I
10.1016/0261-5614(90)90006-E
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Following liver transplantation, the effect of post-operative parenteral nutrition with MCT/LCT (Medium Chain Triglycerides/Long Chain Triglycerides) fat emulsions on the recovery of allografts RES function was investigated in a randomised prospective study of three groups of patients (group I, n = 14: 50 g MCT/LCT fats twice weekly, group II, n = 15: 0.7g/kg body weight per day MCT/LCT fats, group III, n = 17: 1.5 g/kg body weight per day MCT/LCT fats). RES function was assessed using the 99Tc(m)-HSA-MM-Clearance (99mTechnetium-Human serum albumen-Millimicrosphere-Clearance). There were no statistically significant differences in the recovery of RES function between the groups. A negative effect on RES function as a result of the administration of MCT/LCT fat emulsions up to 1.5 g/kg b.w. per day can therefore be excluded. The evaluation of liver biopsies before the administration of fats and at the end of TPN (Total Parenteral Nutrition) showed no evidence, in the 20 patients investigated, of any fatty changes in the liver caused by the infusion of fat.
引用
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页码:331 / 336
页数:6
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