DOUBLE-CHAIN SURFACTANT AS A NEW AND USEFUL MICELLE-FORMING REAGENT FOR MICELLAR ELECTROKINETIC CHROMATOGRAPHY

Disodium 5,12-bis(dodecyloxymethyl)-4,7,10,13-tetraoxa-1,16-hexadecanedisulphonate, a surfactant with two ionic groups and two lipophilic chains, was first utilized in micellar electrokinetic chromatography (MEKC). A good linear relationship was obtained between the capacity factors of several model analytes tested and the concentrations of the surfactant. Compared with widely used sodium dodecyl sulphate, this new surfactant exhibited remarkably different selectivity for several substituted naphthalene and benzene derivatives and gave a wider migration time window. MEKC could be performed at surfactant concentrations at most one order of magnitude lower, because of the low critical micelle concentration.