CHANGES IN SERUM ERYTHROPOIETIN LEVELS DURING CHEMOTHERAPY FOR LUNG-CANCER

被引：8

作者：

SAIJO, Y ^{[1
]}

NAKAI, Y ^{[1
]}

SAITO, J ^{[1
]}

SUGAWARA, S ^{[1
]}

SUZUKI, S ^{[1
]}

NUMATA, Y ^{[1
]}

MOTOMIYA, M ^{[1
]}

机构：

[1] TOHOKU UNIV,TB & CANC RES CTR,DEPT MED,SENDAI,MIYAGI 980,JAPAN

来源：

CHEMOTHERAPY | 1992年 / 38卷 / 05期

关键词：

ERYTHROPOIETIN; CANCER CHEMOTHERAPY; LUNG CANCER;

D O I：

10.1159/000239014

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Serial serum erythropoietin (EPO) levels were measured in 12 adult lung cancer patients during cancer chemotherapy. In major cases, EPO levels increased significantly after chemotherapy while the hemoglobin (Hb) remained at initial levels. EPO fell gradually or rapidly to initial levels after a peak, although the patients were anemic. The increase of EPO levels was linearly related to the decrease in Hb (y = 17.48x + 1.003). The mechanism of the rapid increase of EPO is not simply explained by anemia, but might be related to new synthesis, corresponding to depressed bone marrow.

引用

页码：281 / 285

页数：5

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