LARGER SCALE PREPARATION OF OPTICALLY-ACTIVE ALLYLIC ALCOHOLS

被引：26

作者：

BALMER, E

GERMAIN, A

JACKSON, WP

LYGO, B

机构：

[1] WELLCOME FDN LTD,PROC RES CHEM DEV,B427,TEMPLE HILL,DARTFORD,KENT,ENGLAND

[2] UNIV SALFORD,DEPT CHEM,SALFORD M5 4WT,LANCS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 04期

关键词：

D O I：

10.1039/p19930000399

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and practical synthesis of optically-active allylic alcohols from 2,3-epoxytoluene-p-sulfonates by the in situ formation of the epoxy iodides and their subsequent reduction with zinc-copper couple has been established. Application of this procedure to the larger-scale synthesis of (S)-(+)-but-3-en-2-ol from (2S,3S)-3-methylglycidyl toluene-p-sulfonate has also been investigated.

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页码：399 / 400

页数：2

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