DESIGNED NUCLEOPHILIC-ATTACK BASED ON MOLECULAR ELECTROSTATIC POTENTIAL

被引：9

作者：

KESERU, GM

KAJTARPEREDY, M

NARAYSZABO, G

机构：

[1] EOTVOS LORAND UNIV, DEPT THEORET CHEM, H-1518 BUDAPEST 112, HUNGARY

[2] HUNGARIAN ACAD SCI, CENT RES INST CHEM, H-1521 BUDAPEST, HUNGARY

[3] HUNGARIAN ACAD SCI, RES GRP ALKALOID CHEM, H-1521 BUDAPEST, HUNGARY

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 49期

关键词：

D O I：

10.1016/0040-4039(94)88481-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We describe the computer-aided design of the steric preference in a nucleophilic attack on sterically unbiased carbonyl groups. To our knowledge, this is the first example for the successful application of the molecular electrostatic potential map to computer-assisted synthesis.

引用

收藏

页码：9255 / 9258

页数：4

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