CHARACTERISTICS AND PROGNOSIS OF PRIMARY LIVER-CANCER IN YOUNG-PATIENTS IN CHINA

被引：8

作者：

ZHOU, XD

TANG, ZY

YU, YQ

YANG, BH

LU, JZ

LIN, ZY

ZHANG, BH

机构：

[1] Liver Cancer Institute, Zhong Shan Hospital, Shanghai Medical University, Shanghai

来源：

JOURNAL OF GASTROENTEROLOGY | 1995年 / 30卷 / 05期

关键词：

HEPATOMA; HBV INFECTION; CARCINOGENESIS;

D O I：

10.1007/BF02367790

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

To investigate the clinicopathologic characteristics of primary liver cancer (PLC) in young adults, 77 patients aged 35 or younger were compared with 603 patients older than 35 years during the same period. In the young patients, PLC showed: (1) a low incidence detected at mass survey (young 15.6% vs older 28.7%, P < 0.05); (2) a low level of history of hepatitis (young 36.8% vs older 66.3%, P < 0.01); (3) a high incidence of positivity for hepatitis B surface antigen (HBsAg) (young 79.2% vs older 67.6%, P < 0.05); (4) a relatively low incidence of associated cirrhosis (young 64.9% vs older 90.7%, P < 0.01); (5) larger tumor size (PLC > 5 cm; young 87.0% vs older 73.0%, P < 0.01); and (6) a more advanced stage of the disease according to the TNM classification (stage III; young 29.9% vs older 18.2%, P < 0.05). It is suggested that hepatitis B virus (HBV) may play an important role in the development of PLC without associated liver cirrhosis in young patients. Close periodic surveillance of young adults who are positive for HBsAg is important to detect PLC at an early stage.

引用

页码：632 / 635

页数：4

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