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THE AGONIST PHARMACOPHORE OF THE BENZODIAZEPINE RECEPTOR - SYNTHESIS OF A SELECTIVE ANTICONVULSANT ANXIOLYTIC

被引：39
作者：
DIAZARAUZO, H
EVONIUK, GE
SKOLNICK, P
COOK, JM
机构：
[1] UNIV WISCONSIN,DEPT CHEM,MILWAUKEE,WI 53201
[2] NIDDKD,NEUROSCI LAB,BETHESDA,MD 20892
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1991年 / 34卷 / 05期
关键词：
D O I：
10.1021/jm00109a035
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
[No abstract available]
引用
收藏
页码：1754 / 1756
页数：3
相关论文
共 36 条
  • [1] SYNTHETIC AND COMPUTER-ASSISTED ANALYSES OF THE PHARMACOPHORE FOR THE BENZODIAZEPINE RECEPTOR INVERSE AGONIST SITE
    ALLEN, MS
    TAN, YC
    TRUDELL, ML
    NARAYANAN, K
    SCHINDLER, LR
    MARTIN, MJ
    SCHULTZ, C
    HAGEN, TJ
    KOEHLER, KF
    CODDING, PW
    SKOLNICK, P
    COOK, JM
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (09) : 2343 - 2357
  • [2] BOREA PA, 1986, MOL PHARMACOL, V31, P334
  • [3] LIGANDS FOR BENZODIAZEPINE RECEPTORS WITH POSITIVE AND NEGATIVE EFFICACY
    BRAESTRUP, C
    HONORE, T
    NIELSEN, M
    PETERSEN, EN
    JENSEN, LH
    [J]. BIOCHEMICAL PHARMACOLOGY, 1984, 33 (06) : 859 - 862
  • [4] (IMIDAZO[1,2-A]PYRIMIDIN-2-YL)PHENYLMETHANONES AND RELATED-COMPOUNDS AS POTENTIAL NONSEDATIVE ANXIOLYTICS
    CLEMENTSJEWERY, S
    DANSWAN, G
    GARDNER, CR
    MATHARU, SS
    MURDOCH, R
    TULLY, WR
    WESTWOOD, R
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1988, 31 (06) : 1220 - 1226
  • [5] CODDING PW, 1985, MOL PHARMACOL, V28, P178
  • [6] TRICYCLIC HETEROAROMATIC SYSTEMS - [1]BENZOPYRANOPYRROL-4-ONES AND [1]BENZOPYRANO-1,2,3-TRIAZOL-4-ONES AS BENZODIAZEPINE RECEPTOR LIGANDS - SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS
    COLOTTA, V
    CECCHI, L
    MELANI, F
    FILACCHIONI, G
    MARTINI, C
    GIANNACCINI, G
    LUCACCHINI, A
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (09) : 2646 - 2651
  • [7] CRIPPEN GM, 1982, MOL PHARMACOL, V22, P11
  • [8] DIAZARAUZO H, IN PRESS LIFE SCI
  • [9] SYNTHESIS AND EVALUATION OF A SERIES OF ARYL[E]FUSED PYRAZOLO[4,3-C]PYRIDINES WITH POTENTIAL ANXIOLYTIC ACTIVITY
    FORBES, IT
    JOHNSON, CN
    JONES, GE
    LOUDON, J
    NICHOLASS, JM
    THOMPSON, M
    UPTON, N
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 1990, 33 (09) : 2640 - 2645
  • [10] FRYER RI, 1986, LIFE SCI, V39, P1947
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