SELECTIVE INVITRO GROWTH OF T-LYMPHOCYTES FROM NORMAL HUMAN BONE MARROWS

被引：2418

作者：

MORGAN, DA

RUSCETTI, FW

GALLO, R

机构：

[1] LITTON BIONETICS INC, RES LABS, BETHESDA, MD 20014 USA

[2] NCI, TUMOR CELL BIOL, BETHESDA, MD 20014 USA

来源：

SCIENCE | 1976年 / 193卷 / 4257期

关键词：

D O I：

10.1126/science.181845

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Selective growth of T [thymus-derived] lymphocytes occurred when unfractionated normal human bone marrow cells were cultured with conditioned medium obtained from phytohemagglutinin-stimulated normal human lymphocytes (Ly-CM). Cultures of up to 90% T cells were maintained for more than 9 mo. The T cells exhibited a strict growth dependence upon Ly-CM and were consistently negative for Epstein-Barr viral information.

引用

页码：1007 / 1008

页数：2

共 13 条

[1]

KAPLAN J, 1974, CANCER RES, V34, P521

[2] GENERATION OF CYTOTOXIC T LYMPHOCYTES INVITRO .2. EFFECT OF REPEATED EXPOSURE TO ALLOANTIGENS ON CYTOTOXIC ACTIVITY OF LONG-TERM MIXED LEUKOCYTE-CULTURES [J].