INDOLE ALKALOID PRODUCTION BY HAIRY ROOT CULTURES OF CATHARANTHUS-ROSEUS - GROWTH-KINETICS AND FERMENTATION

被引：27

作者：

TOIVONEN, L

OJALA, M

KAUPPINEN, V

机构：

[1] TECH RES CTR FINLAND,CHEM LAB,SF-02150 ESPOO,FINLAND

[2] TECH RES CTR FINLAND,BIOTECH LAB,SF-02150 ESPOO,FINLAND

来源：

BIOTECHNOLOGY LETTERS | 1990年 / 12卷 / 07期

关键词：

D O I：

10.1007/BF01086346

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Growth kinetics and indole alkaloid production of Catharanthus roseus hairy root cultures were studied in shake flasks and in a small scale fermenter. A logistic growth model commonly used for microbes described well the growth of hairy roots. Of the several parameters analyzed during the cultivation of hairy roots, a linear relationship between sucrose consumption and dry weight increase was obtained. This suggests the validity of sugar analysis as a means in monitoring the growth of hairy roots in fermenters. © 1990 Kluwer Academic Publishers.

引用

页码：519 / 524

页数：6

共 9 条

[1] THIARUBRINE ACCUMULATION IN HAIRY ROOT CULTURES OF CHAENACTIS-DOUGLASII [J].