2-PYRIDINONE DERIVATIVES - A NEW CLASS OF NONNUCLEOSIDE, HIV-1-SPECIFIC REVERSE-TRANSCRIPTASE INHIBITORS

被引：115

作者：

SAARI, WS

HOFFMAN, JM

WAI, JS

FISHER, TE

ROONEY, CS

SMITH, AM

THOMAS, CM

GOLDMAN, ME

OBRIEN, JA

NUNBERG, JH

QUINTERO, JC

SCHLEIF, WA

EMINI, EA

STERN, AM

ANDERSON, PS

机构：

[1] MERCK SHARP & DOHME LTD,DEPT NEW LEAD PHARMACOL,W POINT,PA 19486

[2] MERCK SHARP & DOHME LTD,DEPT VIRUS & CELL BIOL,W POINT,PA 19486

[3] MERCK SHARP & DOHME LTD,DEPT BIOL CHEM,W POINT,PA 19486

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1991年 / 34卷 / 09期

关键词：

D O I：

10.1021/jm00113a036

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

[No abstract available]

引用

页码：2922 / 2925

页数：4

共 14 条

[1] DIDEOXYINOSINE IN CHILDREN WITH SYMPTOMATIC HUMAN-IMMUNODEFICIENCY-VIRUS INFECTION
BUTLER, KM
HUSSON, RN
BALIS, FM
BROUWERS, P
EDDY, J
ELAMIN, D
GRESS, J
HAWKINS, M
JAROSINSKI, P
MOSS, H
POPLACK, D
SANTACROCE, S
VENZON, D
WIENER, L
WOLTERS, P
PIZZO, PA
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (03) : 137 - 144
[2] DOURNON E, 1988, LANCET, V2, P1297
[3] THE EFFICACY OF AZIDOTHYMIDINE (AZT) IN THE TREATMENT OF PATIENTS WITH AIDS AND AIDS-RELATED COMPLEX - A DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
FISCHL, MA
RICHMAN, DD
GRIECO, MH
GOTTLIEB, MS
VOLBERDING, PA
LASKIN, OL
LEEDOM, JM
GROOPMAN, JE
MILDVAN, D
SCHOOLEY, RT
JACKSON, GG
DURACK, DT
KING, D
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1987, 317 (04) : 185 - 191
[4] FREQUENT DETECTION AND ISOLATION OF CYTOPATHIC RETROVIRUSES (HTLV-III) FROM PATIENTS WITH AIDS AND AT RISK FOR AIDS
GALLO, RC
SALAHUDDIN, SZ
POPOVIC, M
SHEARER, GM
KAPLAN, M
HAYNES, BF
PALKER, TJ
REDFIELD, R
OLESKE, J
SAFAI, B
WHITE, G
FOSTER, P
MARKHAM, PD
[J]. SCIENCE, 1984, 224 (4648) : 500 - 503
[5] GOLDMAN ME, 1990, MOL PHARMACOL, V38, P20
[6] GOLDMAN ME, UNPUB HIV 1 SPECIFIC
[7] HIV WITH REDUCED SENSITIVITY TO ZIDOVUDINE (AZT) ISOLATED DURING PROLONGED THERAPY
LARDER, BA
DARBY, G
RICHMAN, DD
[J]. SCIENCE, 1989, 243 (4899) : 1731 - 1734
[8] MULTIPLE MUTATIONS IN HIV-1 REVERSE-TRANSCRIPTASE CONFER HIGH-LEVEL RESISTANCE TO ZIDOVUDINE (AZT)
LARDER, BA
KEMP, SD
[J]. SCIENCE, 1989, 246 (4934) : 1155 - 1158
[9] INHIBITION OF HIV-1 REPLICATION BY A NONNUCLEOSIDE REVERSE-TRANSCRIPTASE INHIBITOR
MERLUZZI, VJ
HARGRAVE, KD
LABADIA, M
GROZINGER, K
SKOOG, M
WU, JC
SHIH, CK
ECKNER, K
HATTOX, S
ADAMS, J
ROSEHTHAL, AS
FAANES, R
ECKNER, RJ
KOUP, RA
SULLIVAN, JL
[J]. SCIENCE, 1990, 250 (4986) : 1411 - 1413
[10] MOLECULAR TARGETS FOR AIDS THERAPY
MITSUYA, H
YARCHOAN, R
BRODER, S
[J]. SCIENCE, 1990, 249 (4976) : 1533 - 1544

← 1 2 →