A DOT-BLOT HYBRIDIZATION PROCEDURE FOR THE DETECTION OF ASTROVIRUS IN STOOL SAMPLES

被引：22

作者：

WILLCOCKS, MM ^{[1
]}

CARTER, MJ ^{[1
]}

SILCOCK, JG ^{[1
]}

MADELEY, CR ^{[1
]}

机构：

[1] ROYAL VICTORIA INFIRM,DEPT VIROL,NEWCASTLE TYNE NE1 1LP,ENGLAND

来源：

EPIDEMIOLOGY AND INFECTION | 1991年 / 107卷 / 02期

关键词：

D O I：

10.1017/S0950268800049049

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We have developed a nucleic acid dot-blot hybridization test for the detection of astroviruses in stool samples. The test was not as sensitive as electron microscopy for the detection of low numbers of well preserved astrovirus particles, but was able to identify astroviruses in stools containing particles of indistinct morphology. In total, this procedure identified astroviruses in more samples than did electron microscopy, and the data indicate that the incidence of astroviruses may be substantially underestimated.

引用

页码：405 / 410

页数：6

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