MELATONIN AND JET-LAG - CONFIRMATORY RESULT USING A SIMPLIFIED PROTOCOL

被引：109

作者：

CLAUSTRAT, B ^{[1
]}

BRUN, J ^{[1
]}

DAVID, M ^{[1
]}

SASSOLAS, G ^{[1
]}

CHAZOT, G ^{[1
]}

机构：

[1] HOP ANTIQUAILLE,SERV NEUROL,F-69321 LYON 1,FRANCE

来源：

BIOLOGICAL PSYCHIATRY | 1992年 / 32卷 / 08期

关键词：

D O I：

10.1016/0006-3223(92)90300-O

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

This study replicates the alleviation of jet-lag with melatonin in a simplified protocol for eastward flight. At 22-n hr (n is the time-lag between the North American departure point and France), subjects took either melatonin (8 mg, n = 15), or placebo (n = 15) on the day of the return flight and for 3 consecutive days. On day 8, self-ratings significantly discriminated between melatonin and placebo for global treatment efficacy, morning fatigue, and evening sleepiness.

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页码：705 / 711

页数：7

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