ELECTROSPRAY-IONIZATION MASS-SPECTROMETRY COUPLED WITH SIZE-EXCLUSION CHROMATOGRAPHY

被引：85

作者：

PROKAI, L ^{[1
]}

SIMONSICK, WJ ^{[1
]}

机构：

[1] DUPONT CO INC,MARSHALL R&D LAB,PHILADELPHIA,PA

来源：

RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 1993年 / 7卷 / 09期

关键词：

D O I：

10.1002/rcm.1290070914

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The coupling of electrospray ionization mass spectrometry with gel permeation chromatography (GPC) has been used for the separation of a commercial polydisperse mixture of octylphenoxypoly(ethoxy)ethanol. Stable electrospray conditions are obtained upon using, as GPC solvent, tetrahydrofuran containing 10(-5)-10(-4) M sodium salt which also provides for the formation of intact molecular ions through cationization. Selected-ion chromatograms of sodiated species allow for the monitoring of the elution profiles of individual oligomers, and can be used for the calibration of the GPC.

引用

页码：853 / 856

页数：4

共 24 条

[1] DESIGN AND PERFORMANCE OF A NOVEL ELECTROSPRAY INTERFACE [J].