THE NUCLEOTIDE-SEQUENCE OF THE MURINE HOX-D3 (HOX-4.1) GENE REVEALS EXTENSIVE IDENTITY WITH THE HUMAN PROTEIN

被引：7

作者：

BROWN, WM

ZHOU, LB

TAYLOR, GR

机构：

[1] RW JOHNSON PHARMACEUT RES INST,SKIN BIOL RES CTR JOHNSON & JOHNSON,RARITAN,NJ 08869

[2] RW JOHNSON PHARMACEUT RES INST,DON MILLS M3C 1L9,ON,CANADA

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1994年 / 1219卷 / 01期

关键词：

NUCLEOTIDE SEQUENCE; MURINE HOX-D3; GENE EXPRESSION; AMINO ACID SEQUENCE;

D O I：

10.1016/0167-4781(94)90276-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We report the sequence of the murine Hox-D3 gene, formerly referred to as Hox-4, Hox-4.1 and Hox-4A. This gene is located on murine chromosome 2 in the Hox-D complex. The predicted Hox-D3 protein comprises 417 amino acids and displays 95% identity to the human protein. We have demonstrated that Hox-D3 is expressed in the skin, kidney and thymus, but not in lung, liver, spleen or stomach.

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页码：219 / 222

页数：4

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