THE GENE ENCODING THE HEAT-STABLE ENTEROTOXIN OF VIBRIO-CHOLERAE IS FLANKED BY 123-BASE PAIR DIRECT REPEATS

被引：39

作者：

OGAWA, A

TAKEDA, T

机构：

[1] NATL CHILDRENS MED RES CTR,DEPT INFECT DIS RES,3-35-31 TAISHIOO,SETAGAYA KU,TOKYO 154,JAPAN

[2] MEIJI COLL PHARM,DEPT MICROBIOL,SETAGAYA KU,TOKYO 154,JAPAN

来源：

MICROBIOLOGY AND IMMUNOLOGY | 1993年 / 37卷 / 08期

关键词：

HEAT-STABLE ENTEROTOXIN; VIBRIO-CHOLERAE; 01; DIRECT REPEAT; VIBRIO-CHOLERAE NON-01;

D O I：

10.1111/j.1348-0421.1993.tb01683.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The heat-stable enterotoxin (01-ST) gene (sto) was cloned from chromosome of the strain GP156 of Vibrio cholerae O1 (Inaba, El Tor) in Escherichia coli K-12, and its nucleotide seqence was determined. The nucleotide sequence of sto was very similar to that of NAG-ST gene (stn) of V. cholerae non-01. Both sto and stn were flanked by 123-base pair direct repeats which had at least 93% homology to one another and included some inverted repeats. All the strains of V. cholerae, V. mimicus, V. metschnikovii, V. hollisae and Yersinia enterocolitica examined by colony hybridization had the direct repeat sequence regardless of ST-gene possession.

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页码：607 / 616

页数：10

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