STEROID-HORMONES ARE MULTIFUNCTIONAL MESSENGERS TO THE BRAIN

被引:90
作者
MCEWEN, BS
机构
[1] Laboratory of Neuroendocrinology, Rockefeller University, New York
基金
美国国家卫生研究院;
关键词
D O I
10.1016/1043-2760(91)90042-L
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Because the brain regulates the endocrine system and also responds to it, the changing environment as well as the experiences of the animal can change and shape properties of hormone-sensitive nerve cells. Depending upon the physiologic status of the organism, the effects of actions of steroid hormones can be trophic or damaging to the nervous system. Future research on the actions of steroids on the brain may advance the notion that the endocrine system has some responsibility for determining the individual traits of an animal in brain function and behavior.
引用
收藏
页码:62 / 67
页数:6
相关论文
共 31 条
[2]   GONADAL-STEROID INDUCTION OF STRUCTURAL SEX-DIFFERENCES IN THE CENTRAL NERVOUS-SYSTEM [J].
ARNOLD, AP ;
GORSKI, RA .
ANNUAL REVIEW OF NEUROSCIENCE, 1984, 7 :413-442
[3]  
BEACH FA, 1948, HORMONES BEHAVIOR ST
[4]   OVARY-DEPENDENT DEGENERATION IN THE HYPOTHALAMIC ARCUATE NUCLEUS [J].
BRAWER, JR ;
SCHIPPER, H ;
NAFTOLIN, F .
ENDOCRINOLOGY, 1980, 107 (01) :274-279
[5]   ULTRASTRUCTURAL-CHANGES IN THE HYPOTHALAMIC VENTROMEDIAL NUCLEUS OF OVARIECTOMIZED RATS AFTER ESTROGEN-TREATMENT [J].
CARRER, HF ;
AOKI, A .
BRAIN RESEARCH, 1982, 240 (02) :221-233
[6]   ESTRADIOL MODULATION OF OXYTOCIN BINDING IN THE VENTROMEDIAL HYPOTHALAMIC NUCLEUS OF MALE AND FEMALE RATS [J].
COIRINI, H ;
JOHNSON, AE ;
MCEWEN, BS .
NEUROENDOCRINOLOGY, 1989, 50 (02) :193-198
[7]   GONADAL-STEROIDS MODIFY DENDRITIC SPINE DENSITY IN VENTROMEDIAL HYPOTHALAMIC NEURONS - A GOLGI-STUDY IN THE ADULT-RAT [J].
FRANKFURT, M ;
GOULD, E ;
WOOLLEY, CS ;
MCEWEN, BS .
NEUROENDOCRINOLOGY, 1990, 51 (05) :530-535
[8]   EFFECTS OF PRENATAL STRESS ON VULNERABILITY TO STRESS IN PREPUBERTAL AND ADULT-RATS [J].
FRIDE, E ;
DAN, Y ;
FELDON, J ;
HALEVY, G ;
WEINSTOCK, M .
PHYSIOLOGY & BEHAVIOR, 1986, 37 (05) :681-687
[10]  
GOULD E, 1990, J NEUROSCI, V10, P1286