LOW-DOSE FLUNARIZINE IN THE PROPHYLAXIS OF MIGRAINE

被引：15

作者：

BASSI, P ^{[1
]}

BRUNATI, L ^{[1
]}

RAPUZZI, B ^{[1
]}

ALBERTI, E ^{[1
]}

MANGONI, A ^{[1
]}

机构：

[1] UNIV MILAN,LUIGI SACCO HOSP,DEPT NEUROL,I-20122 MILAN,ITALY

来源：

HEADACHE | 1992年 / 32卷 / 08期

关键词：

MIGRAINE; FLUNARIZINE; SIDE EFFECTS;

D O I：

10.1111/j.1526-4610.1992.hed3208390.x

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In a period of one year (1990) we selected 40 patients suffering from migraine. For an open randomized study there were 2 groups of patients: the first were treated with 10 mg of flunarizine per day and the second with 3 mg per day. The patients were treated for 4 months consecutively. There were 11 drop outs (27.5%): nine for poor compliance and 2 due to side effects. The efficacy of flunarizine in the prophylaxis of migraine was essentially identical in the two dosage groups while the incidence of side effects was considerably reduced in the patients treated with the lower dose.

引用

页码：390 / 392

页数：3

共 15 条

[1]

BONO G, 1985, CEPHALALGIA, V5, P538

[2]

FLUNARIZINE IN MIGRAINE PROPHYLAXIS - EFFICACY AND TOLERABILITY OF 5 MG AND 10 MG DOSE LEVELS [J].

CENTONZE, V ;

MAGRONE, D ;

VINO, M ;

CAPORALETTI, P ;

ATTOLINI, E ;

CAMPANALE, G ;

ALBANO, O .

CEPHALALGIA, 1990, 10 (01) :17-24

[3]

CHOUZA C, 1986, LANCET, V1, P1303

[4]

DAMATO CC, 1990, J MED, V21, P201

[5]

FLUNARIZINE - A REVIEW OF ITS PHARMACODYNAMIC AND PHARMACOKINETIC PROPERTIES AND THERAPEUTIC USE [J].

HOLMES, B ;

BROGDEN, RN ;

HEEL, RC ;

SPEIGHT, TM ;

AVERY, GS .

DRUGS, 1984, 27 (01) :6-44

[6]

A DOUBLE-BLIND PLACEBO-CONTROLLED PROPHYLACTIC STUDY OF FLUNARIZINE (SIBELIUM) IN MIGRAINE [J].

LOUIS, P .

HEADACHE, 1981, 21 (06) :235-239

[7]

EXTRAPYRAMIDAL SYNDROME AND DEPRESSION INDUCED BY FLUNARIZINE [J].

LUGARESI, A ;

MONTAGNA, P ;

GALLASSI, R ;

LUGARESI, E .

EUROPEAN NEUROLOGY, 1988, 28 (04) :208-211

[8]

FLUNARIZINE (SIBELIUM) IN THE PROPHYLAXIS OF MIGRAINE - AN OPEN, LONG-TERM, MULTICENTER TRIAL [J].

MARTINEZLAGE, JM .

CEPHALALGIA, 1988, 8 :15-20

[9]

MARTINEZLAGE JM, 1988, CEPHALALGIA S8, V8, P10

[10]

FLUNARIZINE IN THE PREVENTION OF CLASSICAL MIGRAINE - A PLACEBO-CONTROLLED EVALUATION [J].

MENTENOPOULOS, G ;

MANAFI, T ;

LOGOTHETIS, J ;

BOSTANTZOPOULOU, S .

CEPHALALGIA, 1985, 5 :135-140

← 1 2 →