DNA TYPING OF EPIDEMIOLOGICALLY-RELATED ISOLATES OF ASPERGILLUS-FUMIGATUS

被引：25

作者：

BIRCH, M

NOLARD, N

SHANKLAND, GS

DENNING, DW

机构：

[1] UNIV MANCHESTER,HOPE HOSP,DEPT MED,SALFORD M6 8HD,LANCS,ENGLAND

[2] INST HYG & EPIDEMIOL,MYCOL SECT,B-1050 BRUSSELS,BELGIUM

[3] REG MYCOL REFERENCE LAB,DEPT DERMATOL,GLASGOW G11 6AQ,LANARK,SCOTLAND

[4] UNIV MANCHESTER,N MANCHESTER GEN HOSP,DEPT TROP MED & INFECT DIS,MONSALL UNIT,MANCHESTER M8 6RB,LANCS,ENGLAND

来源：

EPIDEMIOLOGY AND INFECTION | 1995年 / 114卷 / 01期

关键词：

D O I：

10.1017/S0950268800052018

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Invasive aspergillosis is often nosocomially acquired and carries a high mortality. Molecular typing methods to discriminate isolates have now been developed. Using simple restriction endonuclease (Sal1 and Xho1) digestion of total genomic DNA, we have typed 25 epidemiologically-related isolates of A. fumigatus from six hospital episodes of invasive aspergillosis. Eight DNA types were found and in each case the DNA type matched precisely the epidemiological data. Thus DNA typing of A. fumigatus can provide the means to match isolates from linked sources and distinguish isolates from diverse origins.

引用

页码：161 / 168

页数：8

共 17 条

[1] USE OF RANDOMLY AMPLIFIED POLYMORPHIC DNA MARKERS TO DISTINGUISH ISOLATES OF ASPERGILLUS-FUMIGATUS
AUFAUVREBROWN, A
COHEN, J
HOLDEN, DW
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1992, 30 (11) : 2991 - 2993
[2] BARDANA E. J, 1980, CRC CRIT REV CLIN LA, V13, P21
[3] Barnes A. J., 1993, Reviews in Medical Microbiology, V4, P176
[4] IMMUNOBLOT FINGERPRINTING ASPERGILLUS-FUMIGATUS
BURNIE, JP
MATTHEWS, RC
CLARK, I
MILNE, LJR
[J]. JOURNAL OF IMMUNOLOGICAL METHODS, 1989, 118 (02) : 179 - 186
[5] BURNIE JP, 1992, J CLIN PATHOL, V5, P324
[6] RESTRICTION ENDONUCLEASE ANALYSIS OF TOTAL CELLULAR DNA OF ASPERGILLUS-FUMIGATUS ISOLATES OF GEOGRAPHICALLY AND EPIDEMIOLOGICALLY DIVERSE ORIGIN
DENNING, DW
CLEMONS, KV
HANSON, LH
STEVENS, DA
[J]. JOURNAL OF INFECTIOUS DISEASES, 1990, 162 (05) : 1151 - 1158
[7] PULMONARY ASPERGILLOSIS IN THE ACQUIRED-IMMUNODEFICIENCY-SYNDROME
DENNING, DW
FOLLANSBEE, SE
SCOLARO, M
NORRIS, S
EDELSTEIN, H
STEVENS, DA
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (10) : 654 - 662
[8] DENNING DW, 1991, J MED VET MYCOL, V29, P339
[9] STUDIES ON THE EPIDEMIOLOGY OF ASPERGILLUS-FUMIGATUS INFECTIONS IN A UNIVERSITY HOSPITAL
FANTI, F
CONTI, S
CAMPANI, L
MORACE, G
DETTORI, G
POLONELLI, L
[J]. EUROPEAN JOURNAL OF EPIDEMIOLOGY, 1989, 5 (01) : 8 - 14
[10] DEVELOPMENT OF DNA PROBES FOR FINGERPRINTING ASPERGILLUS-FUMIGATUS
GIRARDIN, H
LATGE, JP
SRIKANTHA, T
MORROW, B
SOLL, DR
[J]. JOURNAL OF CLINICAL MICROBIOLOGY, 1993, 31 (06) : 1547 - 1554

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