ERYTHROCYTE GLUTATHIONE-PEROXIDASE ACTIVITY IN HYPERTENSIVE COMPLICATIONS OF PREGNANCY

被引：26

作者：

UOTILA, J ^{[1
]}

TUIMALA, R ^{[1
]}

PYYKKO, K ^{[1
]}

机构：

[1] UNIV TURKU,INST BIOMED SCI,SF-20500 TURKU 50,FINLAND

来源：

GYNECOLOGIC AND OBSTETRIC INVESTIGATION | 1990年 / 29卷 / 04期

关键词：

Glutathione peroxidase; Preeclampsia; Prostaglandins; Selenium;

D O I：

10.1159/000293330

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Thirty-nine patients with hypertensive complications of pregnancy were analyzed in the third trimester with respect to erythrocyte glutathione peroxidase (GSHPx) activity. Patients with severe or superimposed preeclampsia had significantly higher activities of GSHPx than those with mild preeclampsia. We suggest that a high level of GSHPx in the severe forms of preeclampsia reflects the greatly increased peroxide load generated in this disease and is of compensatory nature, responding to the disturbed peroxide and prostaglandin metabolism. © 1990 S. Karger AG, Basel.

引用

页码：259 / 262

页数：4

共 14 条

[1]

BEHNE D, 1979, J CLIN CHEM CLIN BIO, V17, P133

[2] BLOOD SELENIUM AND GLUTATHIONE-PEROXIDASE ACTIVITY IN PREGNANT-WOMEN - COMPARATIVE ASSAYS IN PRIMATES AND OTHER ANIMALS [J].