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FETAL AND NEONATAL BILE-ACID SYNTHESIS AND METABOLISM - CLINICAL IMPLICATIONS

被引：27
作者：
BALISTRERI, WF
机构：
[1] Children's Hospital Research Foundation, Cincinnati, 45229, Ohio, Elland and Bethesda Avenues
来源：
JOURNAL OF INHERITED METABOLIC DISEASE | 1991年 / 14卷 / 04期
关键词：
D O I：
10.1007/BF01797918
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
It has become apparent that with sophisticated technology we are now able to recognize defective bile acid metabolism in a wide variety of disease states. Recognition of specific aberrations, such as inborn errors in bile acid metabolism manifesting as neonatal cholestasis, offers new opportunities for therapeutic intervention. Future studies should determine the incidence of inborn errors in patients with enigmatic and unexplained liver diseases such as idiopathic neonatal hepatitis.
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页码：459 / 477
页数：19
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