EFFECTS OF THE ANGIOTENSIN CONVERTING-ENZYME-INHIBITOR, BENAZEPRIL, ON THE SINOAORTIC BARORECEPTOR HEART-RATE REFLEX

被引：6

作者：

WEST, JNW

DECRESPIGNY, PCC

STALLARD, TJ

LITTLER, WA

机构：

[1] Department of Cardiovascular Medicine, University of Birmingham, Queen Elizabeth Hospital, Birmingham

来源：

CARDIOVASCULAR DRUGS AND THERAPY | 1991年 / 5卷 / 04期

关键词：

BENAZEPRIL; ANGIOTENSIN CONVERTING ENZYME; SINOAORTIC BARORECEPTOR REFLEX;

D O I：

10.1007/BF03029750

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The effects of monotherapy with the angiotensin converting enzyme inhibitor benazepril (10 mg once daily) on cardiovascular baroreceptor reflexes were determined in 10 patients with essential hypertension using a randomized, double-blind, placebo-controlled, cross-over protocol. Early sino-aortic baroreceptor/heart rate reflex resetting was apparent with acute treatment; this effect persisted throughout the active treatment period. Changes in baroreflex sensitivity did not appear to mediate the hypotensive effect of benazepril.

引用

页码：747 / 751

页数：5

共 17 条

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