LOW-MOLECULAR-WEIGHT HEPARIN (KABI-2165, FRAGMIN) - PHARMACOKINETICS AFTER INTRAVENOUS AND SUBCUTANEOUS ADMINISTRATION IN HUMAN VOLUNTEERS

被引：163

作者：

BRATT, G ^{[1
]}

TORNEBOHM, E ^{[1
]}

WIDLUND, L ^{[1
]}

LOCKNER, D ^{[1
]}

机构：

[1] KABI VITRUM AB,DEPT PHARMACOL R&D,S-11287 STOCKHOLM,SWEDEN

来源：

THROMBOSIS RESEARCH | 1986年 / 42卷 / 05期

关键词：

D O I：

10.1016/0049-3848(86)90340-3

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：613 / 620

页数：8

共 16 条

[1] SUBCUTANEOUS ADMINISTRATION OF HEPARIN - A RANDOMIZED COMPARISON WITH INTRAVENOUS ADMINISTRATION OF HEPARIN TO PATIENTS WITH DEEP-VEIN THROMBOSIS [J].

ANDERSSON, G ;

FAGRELL, B ;

HOLMGREN, K ;

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LJUNGBERG, B ;

NILSSON, E ;

WILHELMSSON, S ;

ZETTERQUIST, S .

THROMBOSIS RESEARCH, 1982, 27 (06) :631-639

[2] AN OBJECTIVE STUDY OF ALTERNATIVE METHODS OF HEPARIN ADMINISTRATION [J].

BENTLEY, PG ;

KAKKAR, VV ;

SCULLY, MF ;

MACGREGOR, IR ;

WEBB, P ;

CHAN, P ;

JONES, N .

THROMBOSIS RESEARCH, 1980, 18 (1-2) :177-187

[3] ANTICOAGULANT EFFECTS OF 2 TYPES OF LOW-MOLECULAR WEIGHT HEPARIN ADMINISTERED SUBCUTANEOUSLY [J].

BERGQVIST, D ;

HEDNER, U ;

SJORIN, E ;

HOLMER, E .

THROMBOSIS RESEARCH, 1983, 32 (04) :381-391

[4] DOSE-DEPENDENT DECREASE IN HEPARIN ELIMINATION [J].

BJORNSSON, TD .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1982, 71 (10) :1186-1188

[5]

BRATT G, 1985, THROMB HAEMOSTASIS, V53, P208

[6]

BRATT G, 1985, THROMB HAEMST, V54

[7] COMPARISON BETWEEN COMMERCIAL HEPARIN, LOW-MOLECULAR WEIGHT HEPARIN AND PENTOSAN POLYSULFATE ON HEMOSTASIS AND PLATELETS INVIVO [J].

ESQUIVEL, CO ;

BERGQVIST, D ;

BJORCK, CG ;

NILSSON, B .

THROMBOSIS RESEARCH, 1982, 28 (03) :389-399

[8] NORMAL AND LOW-MOLECULAR WEIGHT HEPARINS - INTERACTION WITH HUMAN-PLATELETS [J].

FABRIS, F ;

FUSSI, F ;

CASONATO, A ;

VISENTIN, L ;

RANDI, M ;

SMITH, MR ;

GIROLAMI, A .

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 1983, 13 (02) :135-139

[9] ANTICOAGULANT AND ANTITHROMBOTIC EFFECTS OF HEPARIN AND LOW-MOLECULAR WEIGHT HEPARIN FRAGMENTS IN RABBITS [J].

HOLMER, E ;

MATTSSON, C ;

NILSSON, S .

THROMBOSIS RESEARCH, 1982, 25 (06) :475-485

[10] LOW-MOLECULAR-WEIGHT HEPARIN AND PREVENTION OF POSTOPERATIVE DEEP-VEIN THROMBOSIS [J].

KAKKAR, VV ;

DJAZAERI, B ;

FOK, J ;

FLETCHER, M ;

SCULLY, MF ;

WESTWICK, J .

BRITISH MEDICAL JOURNAL, 1982, 284 (6313) :375-380

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