THE NUCLEOLAR SNRNAS - CATCHING UP WITH THE SPLICEOSOMAL SNRNAS

被引：136

作者：

FOURNIER, MJ ^{[1
]}

MAXWELL, ES ^{[1
]}

机构：

[1] N CAROLINA STATE UNIV,DEPT BIOCHEM,RALEIGH,NC 27695

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1993年 / 18卷 / 04期

关键词：

D O I：

10.1016/0968-0004(93)90020-N

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Despite their early discovery, research into the small RNAs associated with the eukaryotic nucleolus (snoRNAs) has lagged behind that of their cousins, the small nuclear RNAs which are known to function in mRNA splicing (spliceosomal snRNAs). Recent progress has now shown that the snoRNAs also occupy a vital niche in the RNA world, participating in the processing of ribosomal RNA. Like the spliceosomal snRNAs, the snoRNAs exist as ribonucleoprotein (RNP) particles which appear to assemble into a large multi-RNA RNP complex for pre-rRNA maturation.

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页码：131 / 135

页数：5

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