IMPROVED GENETICALLY MODIFIED ESCHERICHIA-COLI STRAIN FOR PRESCREENING ANTINEOPLASTIC AGENTS

被引：5

作者：

BARTUS, HR

MIRABELLI, CK

AUERBACH, JI

SHATZMAN, AR

TAYLOR, DP

JOHNSON, RK

ROSENBERG, M

CROOKE, ST

机构：

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1984年 / 25卷 / 05期

关键词：

D O I：

10.1128/AAC.25.5.622

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A genetic modification of E. coli strain BR 513 [a component of the biochemial induction assay used for screening natural products for DNA-damaging components] that displays an expanded spectrum of activity is described. This strain may provide an improved prescreen for detecting natural products that interact with DNA.

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页码：622 / 625

页数：4

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