ORIGINAL REACTIONS OF ALPHA,ALPHA-DITHIO ARYL ALKANES WITH BUTYLLITHIUMS

被引：23

作者：

KRIEF, A

KENDA, B

BARBEAUX, P

机构：

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(00)74368-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Thioacetals derived from aromatic ketones react with butyllithiums already at -78-degrees-C and produce via a reductive process the corresponding alpha-thiobenzyllithiums in high yields. The same reaction also takes place selectively, under suitable conditions, with the thioacetals derived from benzaldehyde on which a competing metallation reaction is also possible. These observations clearly show that the thioacetal functionality is not a suitable protecting group against alkyllithiums for aromatic carbonyl compounds.

引用

页码：2509 / 2512

页数：4

共 28 条

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