EXOCRINE PANCREATIC INSUFFICIENCY IN PRESUMED HEALTHY ELDERLY SUBJECTS

被引：5

作者：

ALMODARIS, FI ^{[1
]}

POWER, MJP ^{[1
]}

MCCONNELL, JG ^{[1
]}

TAYLOR, IC ^{[1
]}

ARMSTRONG, E ^{[1
]}

BUCHANAN, KD ^{[1
]}

机构：

[1] QUEENS UNIV BELFAST,DEPT MED,WELLCOME RES LAB,BELFAST BT7 1NN,ANTRIM,NORTH IRELAND

来源：

AGE AND AGEING | 1992年 / 21卷 / 04期

关键词：

D O I：

10.1093/ageing/21.4.269

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

A pilot study on exocrine pancreatic function, using the 2-day para-aminobenzoic acid (PABA) test, was performed on 21 healthy elderly and 26 healthy young subjects. A PABA excretion index (PEI) < 55 %, indicating moderate to severe exocrine pancreatic insufficiency (EPI), was found in 19 % of the elderly group (95 % confidence limits 5-42 %). While the mean value of the PEI was significantly lower in the elderly compared with the young group (Mann-Whitney Z = 2.8, p < 0.01), there was no significant difference when the elderly subgroup with PEI < 55 % was excluded. There was no evidence of a generalized moderate to severe decline in pancreatic exocrine function with increasing age; a mild to moderate decline cannot be excluded.

引用

页码：269 / 272

页数：4

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