CHIRAL SYNTHESIS OF 3-SUBSTITUTED AND 3,3-DISUBSTITUTED GAMMA-BUTYROLACTONES BY ENANTIOSELECTIVE DEPROTONATION STRATEGY

被引:39
作者
HONDA, T
KIMURA, N
TSUBUKI, M
机构
[1] Institute of Medicinal Chemistry, Hoshi University, Shinagawa-ku, Tokyo, 142
关键词
D O I
10.1016/S0957-4166(00)80347-X
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
Chiral synthesis of 3-substituted and 3,3-disubstituted gamma-butyrolactones was achieved by employing an enantioselective deprotonation of the corresponding cyclobutanone derivatives with chiral bases as a key reaction.
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页码:1475 / 1478
页数:4
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