NEW SYNTHETIC ROUTES TO FURANS AND DIHYDROFURANS FROM 1-PROPARGYLBENZOTRIAZOLE

被引：36

作者：

KATRITZKY, AR

LI, JQ

GORDEEV, MF

机构：

[1] Center for Heterocyclic Compounds, Department of Chemistry, University of Florida, Gainesville

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1993年 / 58卷 / 11期

关键词：

D O I：

10.1021/jo00063a022

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Base-assisted cyclizations of 1-[3-[hydroxy(substituted methyl)]propargyl]benzotriazoles, derived from lithiated 1-propargylbenzotriazole (1) and aromatic aldehydes or ketones, gave 2-arylfurans 5 or 1-(5,5-diaryl-2,5-dihydrofuran-2-yl)benzotriazoles 7, respectively, in high yields. Compounds 7 with Grignard reagents yielded trisubstituted 2,5-dihydrofurans 9.

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页码：3038 / 3041

页数：4

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