A CATALYTIC ANTIBODY ELICITED BY A HAPTEN OF TETRAHEDRAL CARBON-TYPE

被引：19

作者：

KITAZUME, T

TSUKAMOTO, T

YOSHIMURA, K

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 11期

关键词：

D O I：

10.1039/c39940001355

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A monoclonal antibody, elicited by a alpha,alpha,alpha',alpha'-tetrafluoroketone hapten, acted as an enzyme-like catalyst for the hydrolysis of an analogous carbonate, demonstrating that the difluoromethylene unit can been used as an isostere and isoelectronic mimic for the oxygen atom in an ether.

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页码：1355 / 1356

页数：2

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