HIGHLY REGIOSELECTIVE MONOALKYLATION OF KETONES VIA MANGANESE ENOLATES PREPARED FROM MANGANESE AMIDES

被引：20

作者：

CAHIEZ, G

FIGADERE, B

CLERY, P

机构：

[1] Laboratoire de Chimie des Organoéléments, associé au CNRS Université P. et M. Curie, F-75252 Paris Cédex 05

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 19期

关键词：

D O I：

10.1016/S0040-4039(00)76829-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ketones are regioselectively converted to Mn-enolates by treatment with Mn-amides such as Ph(Me)NMnCl in THF at 20 degrees C. Mn-enolates can then be regioselectively monoalkylated in good yields. The formation of di or polyalkylated products is never observed (< 1%).

引用

页码：3065 / 3068

页数：4

共 17 条

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