OTOTOXIC REACTION TO ERYTHROMYCIN

被引：9

作者：

AGUSTI, C

FERRAN, F

GEA, J

PICADO, C

机构：

[1] HOSP CLIN BARCELONA, FAC MED, SERV PNEUMOL, VILLARROEL 170, E-08036 BARCELONA, SPAIN

[2] HOSP CLIN BARCELONA, FAC MED, DEPT OTORHINOLARYNGOL, E-08036 BARCELONA, SPAIN

来源：

ARCHIVES OF INTERNAL MEDICINE | 1991年 / 151卷 / 02期

关键词：

D O I：

10.1001/archinte.151.2.380

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report a case of bilateral hearing loss in a patient treated with intravenous erythromycin lactobionate. The ototoxic reaction occurred despite the patient's having normal renal and hepatic function and the fact that serum erythromycin levels were within the predicted normal range. In addition to hearing loss, a marked labyrinthic hyporreflexia was also observed. Hearing loss improved after the treatment was discontinued, but labyrinthic abnormalities persisted suggesting that erythromycin had caused a permanent vestibular damage.

引用

页码：380 / 380

页数：1

共 5 条

[1] MICROMETHOD FOR ASSAYING SERUM LEVELS OF ERYTHROMYCIN [J].