IMPLEMENTATION OF A MODEL FOR ESTIMATING TUMOR-CONTROL PROBABILITY FOR AN INHOMOGENEOUSLY IRRADIATED TUMOR

被引：156

作者：

NIEMIERKO, A ^{[1
]}

GOITEIN, M ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,BOSTON,MA 02115

来源：

RADIOTHERAPY AND ONCOLOGY | 1993年 / 29卷 / 02期

关键词：

TUMOR CONTROL PROBABILITY; TCP; BIOLOGICAL MODEL; MODELING; TREATMENT PLANNING; OPTIMIZATION;

D O I：

10.1016/0167-8140(93)90239-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

This paper presents the details of a practical implementation of a model for the prediction of the tumor control probability (TCP) when a tumor is irradiated non-uniformly. The implementation is based on a previously published model and represents a simplified version of the model with a limited number (five) of parameters. We show how to derive the model parameters from clinically available data and offer pseudocode for computer implementation. The model should be a useful tool for evaluating and optimizing 3D dose distributions.

引用

页码：140 / 147

页数：8