D21S418E IDENTIFIES A CAMP-REGULATED GENE LOCATED ON CHROMOSOME 21Q22.3 THAT IS EXPRESSED IN PLACENTAL SYNCYTIOTROPHOBLAST AND CHORIOCARCINOMA CELLS

被引：14

作者：

KIDO, S

SAKURAGI, N

BRONNER, MP

SAYEGH, R

BERGER, R

PATTERSON, D

STRAUSS, JF

机构：

[1] UNIV PENN,DEPT OBSTET & GYNECOL,778 CLIN RES BLDG,422 CURIE BLVD,PHILADELPHIA,PA 19104

[2] UNIV PENN,DEPT PATHOL & LAB MED,PHILADELPHIA,PA 19104

[3] ELEANOR ROOSEVELT INST,DENVER,CO 80206

来源：

GENOMICS | 1993年 / 17卷 / 01期

关键词：

D O I：

10.1006/geno.1993.1317

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A partial cDNA (D21S418E) whose nucleotide sequence has no significant homologies with known mammalian DNA sequences was isolated from a human placental library. The cDNA hybridized with a 10-kb transcript present in term placenta. Messages of 10 and 7.5 kb were induced in BeWo and JEG-3 choriocarcinoma cells by treatment with 8-Br-cAMP. The mRNA was not detected in human brain, liver, lung, kidney, pancreas, heart, skeletal muscle, or myometrium. The D21S418E locus was assigned to a 3.5-Mb region of chromosome 21q22.3. © 1993 Academic Press. All rights reserved.

引用

页码：256 / 259

页数：4

共 15 条

[1] HUMAN CHORIONIC-GONADOTROPIN LEVELS IN PREGNANCIES WITH ANEUPLOID FETUSES
BOGART, MH
GOLBUS, MS
SORG, ND
JONES, OW
[J]. PRENATAL DIAGNOSIS, 1989, 9 (06) : 379 - 384
[2] BOUE J, 1981, TRISOMY 21, P183
[3] COUTIFARIS C, 1991, DEVELOPMENT, V113, P767
[4] EPSTEIN CJ, 1991, AM J HUM GENET, V49, P207
[5] GAFVELS ME, 1992, J BIOL CHEM, V267, P21230
[6] ANALYSIS OF HUMAN CHROMOSOME-21 - CORRELATION OF PHYSICAL AND CYTOGENETIC MAPS - GENE AND CPG ISLAND DISTRIBUTIONS
GARDINER, K
HORISBERGER, M
KRAUS, J
TANTRAVAHI, U
KORENBERG, J
RAO, V
REDDY, S
PATTERSON, D
[J]. EMBO JOURNAL, 1990, 9 (01) : 25 - 34
[7] IRRADIATION-REDUCED HUMAN CHROMOSOME-21 HYBRIDS
GRAW, S
DAVIDSON, J
GUSELLA, J
WATKINS, P
TANZI, R
NEVE, R
PATTERSON, D
[J]. SOMATIC CELL AND MOLECULAR GENETICS, 1988, 14 (03) : 233 - 242
[8] KORENBERG JR, 1990, AM J HUM GENET, V47, P236
[9] SEQUENTIAL STAINING TECHNIQUE FOR CHROMOSOMAL ANALYSIS OF INTERSPECIFIC MOUSE-HAMSTER AND MOUSE-HUMAN SOMATIC-CELL HYBRIDS
KOZAK, CA
LAWRENCE, JB
RUDDLE, FH
[J]. EXPERIMENTAL CELL RESEARCH, 1977, 105 (01) : 109 - 117
[10] SUBLOCALIZATION ON CHROMOSOME-21 OF HUMAN INTERFERON-ALPHA RECEPTOR GENE AND THE GENE FOR AN INTERFERON-GAMMA RESPONSE PROTEIN
LANGER, JA
RASHIDBAIGI, A
LAI, LW
PATTERSON, D
JONES, C
[J]. SOMATIC CELL AND MOLECULAR GENETICS, 1990, 16 (03) : 231 - 240

← 1 2 →