REACTIONS OF 9-SUBSTITUTED 1-AMINOADENINES WITH NUCLEOPHILES AND SYNTHESES OF 3-SUBSTITUTED 3H-IMIDAZO[4,5-E][1,2,4]TRIAZOLO[1,5-C][1,2,3]TRIAZINES

被引：8

作者：

ASANO, S

ITANO, K

YAMAGATA, Y

KOHDA, K

机构：

[1] NAGOYA CITY UNIV,FAC PHARMACEUT SCI,MIZUHO KU,NAGOYA,AICHI 467,JAPAN

[2] OSAKA UNIV,FAC PHARMACEUT SCI,SUITA,OSAKA 565,JAPAN

来源：

NUCLEOSIDES & NUCLEOTIDES | 1994年 / 13卷 / 6-7期

关键词：

D O I：

10.1080/15257779408012163

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Reactions of 1-aminoadenines (2) with NH2OH gave adenine 1-oxides (6). Alkaline treatment of 2 afforded 5-amino-4-(1,2,4-triazol-3-yl)imidazoles (3), which were converted to 3H-imidazo[4,5-e][1,2,4]triazolo[1,5-c][1,2,3]triazines (5), aza analogues o 3H-[1,2,4]triazolo[3,2-i]purines (4), by treatment with NaNO2.

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页码：1453 / 1465

页数：13

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