THE EFFECT OF SURGICAL-TREATMENT ON SURVIVAL FROM EARLY LUNG-CANCER - IMPLICATIONS FOR SCREENING

被引:258
作者
FLEHINGER, BJ
KIMMEL, M
MELAMED, MR
机构
[1] RICE UNIV,DEPT STAT,HOUSTON,TX 77251
[2] NEW YORK MED COLL,DEPT PATHOL,VALHALLA,NY 10595
关键词
D O I
10.1378/chest.101.4.1013
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
We assessed the effect of surgery on survival from stage I non-small-cell lung cancer based on data collected in these screening programs. The majority of patients diagnosed in each program were treated by surgical resection, but 5 percent of the Sloan-Kettering group, 21 percent of the Hopkins group and 11 percent of the Mayo group failed to receive surgical treatment. Appoximately 70 percent of the stage I patients in each program who were treated surgically survived more than five years, but there were only two five-year survivors among those who did not have surgery. We conclude that patients with lung cancers detected in stage I by chest x-ray film and treated surgically have a good chance of remaining free of disease for many years. Those stage I lung cancers which are not resected progress and lead to death within five years. Therefore, every effort should be made to detect and treat lung cancer early in high-risk populations.
引用
收藏
页码:1013 / 1018
页数:6
相关论文
共 14 条
[1]  
BERLIN NI, 1984, AM REV RESPIR DIS, V130, P545
[2]   EARLIER DIAGNOSIS AND SURVIVAL IN LUNG CANCER [J].
BRETT, GZ .
BRITISH MEDICAL JOURNAL, 1969, 4 (5678) :260-&
[3]   SCREENING FOR LUNG-CANCER [J].
EDDY, DM .
ANNALS OF INTERNAL MEDICINE, 1989, 111 (03) :232-237
[4]   NATURAL-HISTORY OF ADENOCARCINOMA LARGE CELL-CARCINOMA OF THE LUNG - CONCLUSIONS FROM SCREENING PROGRAMS IN NEW-YORK AND BALTIMORE [J].
FLEHINGER, BJ ;
KIMMEL, M ;
MELAMED, MR .
JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1988, 80 (05) :337-344
[5]  
FLEHINGER BJ, 1984, AM REV RESPIR DIS, V130, P555
[6]  
FLEHINGER BJ, 1987, BIOMETRICS, V43, P44
[7]   LUNG-CANCER SCREENING - THE MAYO PROGRAM [J].
FONTANA, RS ;
SANDERSON, DR ;
WOOLNER, LB ;
TAYLOR, WF ;
MILLER, WE ;
MUHM, JR .
JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE, 1986, 28 (08) :746-750
[8]  
FONTANA RS, 1984, AM REV RESPIR DIS, V130, P561
[9]  
FROST JK, 1984, AM REV RESPIR DIS, V130, P549
[10]  
MELAMD MR, 1990, DEBATES MED, V3, P120