TERPESTACIN, A NOVEL SYNCYTIUM FORMATION INHIBITOR, ISOLATED FROM ARTHRINIUM SPECIES

被引：36

作者：

IIMURA, S

OKA, M

NARITA, Y

KONISHI, M

KAKISAWA, H

GAO, Q

OKI, T

机构：

[1] BRISTOL MYERS SQUIBB CO,RES INST,2-9-3 SHIMO MEGURO,MEGURO KU,TOKYO 153,JAPAN

[2] TSUCHIURA JR COLL,TSUCHIURA,IBARAKI 300,JAPAN

[3] BRISTOL MYERS SQUIBB CO,RES INST,WALLINGFORD,CT 06492

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 03期

关键词：

TERPESTACIN; COMPLETE STRUCTURE; ARTHRINIUM SP; SYNCYTIUM FORMATION INHIBITOR; BIOSYNTHESIS;

D O I：

10.1016/0040-4039(93)85110-I

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Terpestacin a novel syncytium formation inhibitor in HIV infection, was isolated from Arthrinium sp. metabolites. The structure of terpestacin including the absolute stereochemistry was determined on the basis of spectroscopic analysis and chemical reactions. The biosynthetic pathway of terpestacin was also determined.

引用

页码：493 / 496

页数：4

共 8 条

[1] DECLERCQ E, 1990, DESIGN ANTI AIDS DRU
[2] A NOVEL SYNTHESIS OF DIHYDROJASMONE
ERICKSON, JL
COLLINS, FE
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1965, 30 (04) : 1050 - +
[3] Harada N., 1983, CIRCULAR DICHROIC SP
[4] KANEDA M, 1972, TETRAHEDRON LETT, P4609
[5] STEREOISOMERS OF 3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE
NISHINO, C
BOWERS, WS
[J]. TETRAHEDRON, 1976, 32 (23) : 2875 - 2877
[6] Silverstein R.M., 1974, SPECTROMETRIC IDENTI, P211
[7] VARICULANOL - STRUCTURE AND ABSOLUTE STEREOCHEMISTRY OF A NOVEL 5/12/5 TRICYCLIC SESTERTERPENOID FROM ASPERGILLUS-VARIECOLOR
SINGH, SB
REAMER, RA
ZINK, D
SCHMATZ, D
DOMBROWSKI, A
GOETZ, MA
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (19) : 5618 - 5622
[8] ON THE USE OF THE O-METHYLMANDELATE ESTER FOR ESTABLISHMENT OF ABSOLUTE-CONFIGURATION OF SECONDARY ALCOHOLS
TROST, BM
BELLETIRE, JL
GODLESKI, S
MCDOUGAL, PG
BALKOVEC, JM
BALDWIN, JJ
CHRISTY, ME
PONTICELLO, GS
VARGA, SL
SPRINGER, JP
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (12) : 2370 - 2374

← 1 →