INVITRO ACTIVITY OF L-OFLOXACIN AGAINST NORFLOXACIN-RESISTANT COAGULASE-NEGATIVE STAPHYLOCOCCI

被引：6

作者：

FOLENO, B ^{[1
]}

FU, KP ^{[1
]}

机构：

[1] RW JOHNSON PHARMACEUT RES INST,MICROBIOL RES,RARITAN,NJ 08869

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 1992年 / 15卷 / 06期

关键词：

D O I：

10.1016/0732-8893(92)90109-7

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

The in vitro activity of 1-ofloxacin was determined against coagulase-negative staphylococci that were induced to norfloxacin resistance. 1-Ofloxacin was the most active agent tested with an MIC90 of 4-mu-g/ml compared with >128, 32, and 128-mu-g/ml for norfloxacin, ciprofloxacin, and enoxacin, respectively. Rifampin-resistant, coagulase-negative staphylococci were not cross-resistant to the quinolones tested. Among the rifampin-resistant organisms tested, 1-ofloxacin was also the most active agent with an MIC90 of 0.25-mu-g/ml.

引用

页码：557 / 559

页数：3

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