FRACTALS IN BIOLOGY AND MEDICINE

被引:111
作者
HAVLIN, S
BULDYREV, SV
GOLDBERGER, AL
MANTEGNA, RN
OSSADNIK, SM
PENG, CK
SIMON, M
STANLEY, HE
机构
[1] BOSTON UNIV, DEPT PHYS, BOSTON, MA 02215 USA
[2] BAR ILAN UNIV, DEPT PHYS, RAMAT GAN, ISRAEL
[3] HARVARD UNIV, BETH ISRAEL HOSP, SCH MED, DIV CARDIOVASC, BOSTON, MA 02215 USA
[4] MIT, DEPT BIOL, CAMBRIDGE, MA 02139 USA
基金
美国国家科学基金会; 美国国家航空航天局;
关键词
D O I
10.1016/0960-0779(95)80025-C
中图分类号
O1 [数学];
学科分类号
0701 [数学]; 070101 [基础数学];
摘要
Our purpose is to describe some recent progress in applying fractal concepts to systems of relevance to biology and medicine. We review several biological systems characterized by fractal geometry, with a particular focus on the long-range power-law correlations found recently in DNA sequences containing noncoding material. Furthermore, we discuss the finding that the exponent ct quantifying these long-range correlations (''fractal complexity'') is smaller for coding than for noncoding sequences. We also discuss the application of fractal scaling analysis to the dynamics of heartbeat regulation, and report the recent finding that the normal heart is characterized by long-range ''anticorrelations'' which are absent in the diseased heart.
引用
收藏
页码:171 / 201
页数:31
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