TOPICAL VANCOMYCIN FOR THE TREATMENT OF STAPHYLOCOCCUS-EPIDERMIDIS AND METHICILLIN-RESISTANT STAPHYLOCOCCUS-AUREUS CONJUNCTIVITIS

Staphylococcus aureus and Staphylococcus epidermidis are organisms that frequently cause conjunctivitis or blepharoconjunctivitis. We describe a patient with methicillin-resistant S. aureus and S. epidermidis conjunctivitis who was treated successfully using an extremporaneously prepared topical opthalmic solution of vancomycin hydrochloride 31 mg/mL. Studies describing the preparation, stbility, and comfort of this solution, as well as reports pertaining to efficacy, are reviewed. Controlled clinical trials evaluating the safety and efficacy of vancomycin opthalmic solution have not yet been performed.