THE EFFECT OF RELATIVES ON THE LIKELIHOOD RATIO ASSOCIATED WITH DNA PROFILE EVIDENCE IN CRIMINAL-CASES

被引:19
作者
BROOKFIELD, J [1 ]
机构
[1] UNIV NOTTINGHAM HOSP, QUEENS MED CTR, DEPT GENET, NOTTINGHAM NG7 2UH, ENGLAND
来源
JOURNAL OF THE FORENSIC SCIENCE SOCIETY | 1994年 / 34卷 / 03期
关键词
DNA PROFILING; GENETIC RELATEDNESS; LIKELIHOOD RATIOS;
D O I
10.1016/S0015-7368(94)72914-5
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
In DNA profiling sometimes a match is declared between the DNA profile from a suspect and that from a scene-of-crime DNA sample. DNA evidence has frequently been presented in the form of a likelihood ratio, the ratio of the probabilities of the data set under the two hypotheses of a single and two sources for the matching DNA profiles. The calculation of the probability of a match is usually performed using a product rule with information from an appropriate database. This approach has been criticized for failing to allow for genetic relatedness, such that the suspect could be a close relative of the source of the scene-of-crime DNA profile. This paper suggests ways of incorporating the possibility of relatives into the likelihood ratio, and shows that unless there is strong evidence implicating a full sibling of the accused, allowing for possible relatedness has very little impact.
引用
收藏
页码:193 / 197
页数:5
相关论文
共 15 条
  • [1] Berry DA, 1992, APPL STAT, V41, P499, DOI 10.1111/j.1467-9876.1992/tb02418.x
  • [2] THE EFFECT OF POPULATION SUBDIVISION ON ESTIMATES OF THE LIKELIHOOD RATIO IN CRIMINAL-CASES USING SINGLE-LOCUS DNA PROBES
    BROOKFIELD, J
    [J]. HEREDITY, 1992, 69 : 97 - 100
  • [3] COTTERMAN C. W., 1940, THESIS OHIO STATE U
  • [4] The variant call format and VCFtools
    Danecek, Petr
    Auton, Adam
    Abecasis, Goncalo
    Albers, Cornelis A.
    Banks, Eric
    DePristo, Mark A.
    Handsaker, Robert E.
    Lunter, Gerton
    Marth, Gabor T.
    Sherry, Stephen T.
    McVean, Gilean
    Durbin, Richard
    [J]. BIOINFORMATICS, 2011, 27 (15) : 2156 - 2158
  • [5] EVALUATING DNA PROFILES IN A CASE WHERE THE DEFENSE IS IT WAS MY BROTHER
    EVETT, I
    [J]. JOURNAL OF THE FORENSIC SCIENCE SOCIETY, 1992, 32 (01): : 5 - 14
  • [6] AN EFFICIENT STATISTICAL PROCEDURE FOR INTERPRETING DNA SINGLE LOCUS PROFILING DATA IN CRIME CASES
    EVETT, IW
    SCRANAGE, JK
    PINCHIN, R
    [J]. JOURNAL OF THE FORENSIC SCIENCE SOCIETY, 1992, 32 (04): : 307 - 326
  • [7] EVETT IW, IN PRESS AM J HUMAN
  • [8] GENETIC-DIFFERENCES AT 4 DNA TYPING LOCI IN FINNISH, ITALIAN, AND MIXED CAUCASIAN POPULATIONS
    KRANE, DE
    ALLEN, RW
    SAWYER, SA
    PETROV, DA
    HARTL, DL
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (22) : 10583 - 10587
  • [9] POPULATION-GENETICS IN FORENSIC DNA TYPING
    LEWONTIN, RC
    HARTL, DL
    [J]. SCIENCE, 1991, 254 (5039) : 1745 - 1750
  • [10] GENETIC-STRUCTURE OF FORENSIC POPULATIONS
    MORTON, NE
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (07) : 2556 - 2560