The Role of Bile Acid Excretion in Atherosclerotic Coronary Artery Disease

被引：64

作者：

Charach, Gideon ^{[1
]}

Rabinovich, Alexander ^{[1
]}

Argov, Ori ^{[1
]}

Weintraub, Moshe ^{[1
]}

Rabinovich, Pavel ^{[1
]}

机构：

[1] Tel Aviv Sourasky Med Ctr, Dept Internal Med C, IL-64239 Tel Aviv, Israel

来源：

INTERNATIONAL JOURNAL OF VASCULAR MEDICINE | 2012年 / 2012卷

关键词：

D O I：

10.1155/2012/949672

中图分类号：

R6 [外科学];

学科分类号：

1002 [临床医学]; 100210 [外科学];

摘要：

The impact of cholesterol and different classes of lipoproteins on the development of coronary artery disease (CAD) has been investigated in extensively during the past 50 years. The cholesterol metabolism is dependent on numerous factors, including dietary fat, fractional absorption of dietary cholesterol, tissue stores of cholesterol, endogenous cholesterol synthesis, and fecal bile excretion. Several studies showed significantly lower amounts of bile acid secretion in adult patients with CAD compared to non-CAD patients. Could it be that the inability to efficiently excrete bile acids may lead to CAD development?

引用

页数：3

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