DOPAMINE TREATMENT FOR SEVERE OVARIAN HYPERSTIMULATION SYNDROME

被引:61
作者
FERRARETTI, AP
GIANAROLI, L
DIOTALLEVI, L
FESTI, C
TROUNSON, A
机构
[1] IVF Centre, 40136 Bologna, Via Castiglione
[2] Clinique de Stérilité et d'Endocrinologie Gynécologique, Université de Genéve, Genèeve,1211, 32, Boulevard de le Cluse
[3] Centre for Early Human Development, Monash Medical Centre, Clayton, VIC 3168
关键词
DOPAMINE; OVARIAN HYPERSTIMULATION SYNDROME;
D O I
10.1093/oxfordjournals.humrep.a137613
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Seven oliguric patients with severe ovarian hyperstimulation syndrome following gonadotrophin treatment for in-vitro fertilization or gamete intra-Fallopian transfer, were treated with low doses of dopamine by peripheral infusion. Five patients were pregnant. The rationale for this therapeutic approach was to increase renal blood flow and glomerular filtration. In addition to dopamine, fluid intake was restricted to 500 ml/day and a protein and salt-rich diet was provided in order to increase serum osmolarity. Within 24-48 h from the beginning of the dopamine treatment, the syndrome started to regress in all cases. No adverse maternal or fetal effects occurred. We conclude that dopamine therapy may constitute a major advance towards the management of severe ovarian hyperstimulation syndrome.
引用
收藏
页码:180 / 183
页数:4
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