RAPID DYNAMIC CT SCANNING IN PRIMARY DEGENERATIVE DEMENTIA AND AGE-MATCHED CONTROLS

被引：15

作者：

DYSKEN, MW ^{[1
]}

NELSON, MJ ^{[1
]}

HOOVER, KM ^{[1
]}

KUSKOWSKI, M ^{[1
]}

MCGEACHIE, R ^{[1
]}

机构：

[1] VET ADM MED CTR,DEPT RADIOL,MINNEAPOLIS,MN 55417

来源：

BIOLOGICAL PSYCHIATRY | 1990年 / 28卷 / 05期

关键词：

D O I：

10.1016/0006-3223(90)90410-4

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Dynamic computed tomography (CT) scanning of the brain was performed in 26 patients with primary degenerative dementia (PDD) and in 15 age-matched controls without evidence of a dementing illness. Changes in CT density values over time were obtained for 16 regions of interest (ROIs) that were carefully chosen to avoid overlap with adjacent cerebrospinal fluid (CSF), sulsi, or bone. CT density washout curves were compared between patients and controls to detect regions where blood brain barrier (BBB) permeability might be increased. although the patient's washout curves declined more gradually than control curves in 11 of the 14 ROIs with a functioning BBB, in no case did the difference reach statistical significance. Intrarater correlation coefficients indicated good overall reliability in the selection of ROIs. © 1990.

引用

页码：425 / 434

页数：10

共 23 条

[1]

ALBUMIN AND IMMUNOGLOBULIN IN PLASMA AND CEREBROSPINAL-FLUID, AND BLOOD-CEREBROSPINAL FLUID BARRIER FUNCTION IN PATIENTS WITH DEMENTIA OF ALZHEIMER TYPE AND MULTI-INFARCT DEMENTIA [J].